Biology › Section E · Cell communication and the cell cycle › Topic E.2

Passing on and responding to a signal

A ligand binding its receptor is only the handshake. What follows is the conversation: a relay of shape changes, phosphate tags, and small messengers that carries the signal through the cytoplasm, amplifies it, and ends in a handful of responses - a new protein, a burst of fuel, cell division, or the cell's own orderly death.

In this topic

  • From binding to a cascade
  • Phosphorylation: the cell's sticky notes
  • Second messengers: calcium and cAMP
  • Second messengers: IP3 and DAG
  • Response: new proteins
  • Response: a burst of fuel
  • Response: divide - or not
  • Response: programmed death
  • Worked example: dye in the dish
  • Worked example: the locked switch
  • Common mistakes to avoid
  • Key takeaways

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