Biology › Section E · Cell communication and the cell cycle › Topic E.1

Signaling molecules and receptors

Cells have no mouths, so they talk in chemistry: one cell releases a small molecule, and only cells carrying the matching receptor respond. Here you will meet the four ways signals travel - to nearby cells, distant cells, the cell itself, and straight through junctions between neighbors - and the two kinds of receptors, internal and cell-surface, that turn a molecular handshake into action.

In this topic

  • Cells talk in chemistry
  • Paracrine signaling: talk to your neighbors
  • Endocrine signaling: talk to the whole body
  • Autocrine signaling and direct contact
  • Internal receptors: straight to the genes
  • Cell-surface receptors: the gatekeepers
  • Ion channels and G proteins
  • Enzyme-linked receptors: the tyrosine kinase
  • Worked example: how a virus picks its host
  • Worked example: cholera's locked-on switch
  • Common mistakes to avoid
  • Key takeaways

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