Biology › Section G · Chromosomes and DNA › Topic G.1

Chromosomal theory and gene linkage

Mendel described genes without ever seeing one. A generation later, microscopes caught chromosomes behaving exactly as his 'unit factors' had to - and fruit flies, corn, and one undergraduate's all-nighter turned abstract ratios into physical maps of genes lined up along chromosomes.

In this topic

  • Chromosomes carry the genes
  • Why the theory fits Mendel
  • Morgan's flies settle the argument
  • Crossing over unlinks alleles
  • Parental and nonparental gametes
  • Recombination frequency measures distance
  • Sturtevant's all-nighter
  • The 0 to 50 percent scale
  • Worked example: reading a test cross
  • Worked example: ordering three genes
  • Common mistakes to avoid
  • Key takeaways

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