Biology › Section O · Hormones, bones, and muscles › Topic O.7

Muscle contraction and locomotion

Every step, heartbeat and breath depends on protein filaments sliding past one another. Following a skeletal muscle from the nerve signal to the pull on a bone shows how electricity, calcium and ATP combine to make movement.

In this topic

  • From signal to movement
  • Inside a muscle fibre
  • The sarcomere
  • Thick and thin filaments
  • The sliding filament model
  • Worked example: measuring a contracting sarcomere
  • The cross-bridge cycle
  • From nerve impulse to calcium
  • Controlling force
  • Worked example: predicting the effect of a toxin
  • Common mistakes to avoid
  • Key takeaways

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