Anatomy & Physiology › Section W · The urinary system › Topic W.4

Regulation of renal blood flow and kidney function

Your blood pressure swings every time you stand, sleep or exercise, yet your filtration rate barely moves. This topic explains the local mechanisms that steady kidney blood flow, and the nerves and hormones that override them to defend blood pressure, blood volume and the body's salt and water.

In this topic

  • Why filtration must be steady
  • The myogenic mechanism
  • Tubuloglomerular feedback
  • Worked example: is the pressure in range?
  • Sympathetic control
  • The renin-angiotensin-aldosterone system
  • Aldosterone and ADH
  • Natriuretic peptides
  • Other regulators
  • Worked example: responding to blood loss
  • Common mistakes to avoid
  • Key takeaways

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