Anatomy & Physiology › Section Y · Reproduction and development › Topic Y.4

Fertilization

Fertilisation joins one sperm and one oocyte into a single cell with a full set of chromosomes. Getting there means surviving a hostile journey, being chemically primed, cutting through two protective layers and then shutting the door on every other sperm.

In this topic

  • What fertilisation achieves
  • A journey that thins the crowd
  • How long each gamete survives
  • Worked example: the length of the fertile window
  • Capacitation: priming the sperm
  • Crossing the corona radiata and zona pellucida
  • Blocking extra sperm
  • Worked example: counting chromosomes
  • From pronuclei to zygote
  • Twins and fertilisation outside the body
  • Common mistakes to avoid
  • Key takeaways

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